GLP-1s (short for glucagon-like peptide-1 receptor agonists) are medications that help with weight loss and blood sugar control. They work by copying a hormone your body already makes, called GLP-1, which helps regulate appetite, digestion, and insulin levels.
Think of GLP-1s like a helpful coach for your body:
GLP-1s were first introduced as diabetes medications in the early 2000s. Scientists noticed that patients taking them also lost weight, so they started studying them for obesity treatment. In 2021, the first GLP-1 specifically for weight loss was approved. Now, they’re one of the most popular weight loss options available!
GLP-1 medications aren’t a magic fix, but they can make weight loss easier by reducing hunger and helping your body work with you instead of against you. Today, GLP-1s are used by:
If you’ve struggled with weight loss in the past, talking to your doctor about GLP-1s could be an important next step. Or, speak with one of the providers listed on TelemedsForMe.
A: Yes, GLP-1s have been studied for years and are FDA-approved for weight loss and diabetes. Like any medication, they can have side effects, such as nausea or stomach discomfort, but many people find these improve over time, especially with proper nutrition and changes in diet.
A: Not necessarily. Some people take GLP-1s long-term, while others stop once they reach their goal weight. However, maintaining weight loss after stopping the medication may require continued lifestyle changes.
A: It depends. The BMI (Body Mass Index) requirements for GLP-1 medications depend on the specific drug and its approved use. For weight loss: BMI of 30 or higher (classified as obesity), OR BMI of 27 or higher (overweight) with at least one weight-related health condition (such as Type 2 diabetes, high blood pressure, or sleep apnea).
A: GLP-1 injections are typically given just under the skin (subcutaneous injection) in one of three areas: in the upper part of the thigh; in the stomach, at least 2 inches away from your belly button; or in the back of the upper arm. (This last location is hard to do on your own!)
A: Most people tolerate GLP-1s well, but some may experience side effects, especially when first starting. Mild side effects can include nausea, vomiting, diarrhea, constipation, bloating, stomach discomfort, and decreased appetite. Less common but serious side effects include severe stomach pain, gallbladder issues, low blood sugar, and allergic reactions. You can help mitigate GLP-1 side effects by eating smaller meals, avoiding greasy foods, staying hydrated, and keeping your doctor informed if side effects worsen.
The cast of Wicked: For Good dazzled in early promotional photos — but not for the reasons anyone expected. Instead of discussions about acting, choreography, or cinematic magic, social media conversations centered on something far more concerning: When Thin Isn’t a Win.
For years, GLP-1 medications such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have been known for their powerful effects on appetite control, blood sugar regulation, and weight loss. But new research reveals a surprising frontier: GLP-1 drugs may also influence addiction pathways, including those related to smoking, tobacco use, nicotine dependence, alcohol misuse, and opioid addiction.
For decades, opioid addiction has ravaged lives and communities. The combination of dependence, relapse risk, and overdose deaths has made finding new, effective treatments a public health priority. Emerging research now suggests that GLP-1 receptor agonists — drugs originally developed to treat type 2 diabetes and obesity — may play a surprising role in reducing opioid cravings and substance abuse behaviors. GLP-1 & Opioid Addiction.
